DERBIOME® PDRN
(Polydeoxyribonucleotide)
DERBIOME® PDRN is a patented low-molecular DNA ingredient derived from ethically sourced Korean salmon DNA, developed to support visible skin renewal, elasticity, and overall skin quality improvement.
Inspired by regenerative technologies used in Korean aesthetic clinics, DERBIOME® PDRN utilizes advanced purification and molecular optimization technology for enhanced cosmetic skin compatibility.
Unlike traditional skincare ingredients focused only on surface hydration, DERBIOME® PDRN is designed to support skin quality at the structural level—helping improve the appearance of weakened, fatigued, and aging skin over time.
Advanced Korean PDRN Technology
DERBIOME® PDRN utilizes an optimized low-molecular DNA fragmentation process designed to support skin compatibility and advanced skin-conditioning performance.
Internal in-vitro testing demonstrated support for:
• smoother-looking texture
• visible elasticity
• healthier-looking skin
• refined radiance
• improved skin resilience
Exosome Technology
We use plant-derived exosome-like nanovesicles (30–200 nm) as elegant biological messengers and delivery shuttles for actives. Literature suggests exosomes can carry peptides, nucleic acids, and lipids that modulate inflammation and tissue repair; plant-derived exosome-like vesicles are being explored as biocompatible, low-immunogenic nanocarriers with potential in skin regeneration and barrier homeostasis. (Research is active; standardization/clinical endpoints are still evolving.)
CISL Triple Peptide (3X)
Our Triple Peptide Capsule System combines signal peptides such as Palmitoyl Tripeptide-1 to stimulate new collagen and reorganize the dermal matrix, carrier peptides like GHK-Cu to activate reparative gene expression and support collagen and glycosaminoglycan turnover, and neuropeptides such as Acetyl Hexapeptide-8 to relax expression lines by modulating the SNARE complex. Working together in a micro-encapsulated delivery system, these peptides synergistically strengthen the extracellular matrix, ease surface stress, and ultimately support barrier recovery—leaving skin smoother, more resilient, and better protected over time.
A New Way to Pair PDRN + Matrixyl™ 3000 (10%)
Matrixyl™ 3000 is a well-recognized peptide duo that signals the skin to restore collagen and resilience. At CISL SEOUL, we go beyond simply adding this ingredient—we precisely pair Matrixyl™ 3000 (10%) with our signature PDRN and advanced exosome delivery system. This unique combination harmonizes signal (collagen stimulation), repair (ECM regeneration), and communication (enhanced delivery and bio-stability), creating a synergistic effect that elevates wrinkle correction to a new standard.