4.8 · 105 reviews

DUAL-CHAMBER REJUVENATION TREATMENT

DUAL INFUSHOT™ REJUVENATION SERUM

Smoother-looking texture. Firmer-looking skin. Restored radiance.

PDRN rejuvenation + retinoid renewal — powered by DERBIOME® PDRN.

$119· 50 mL / 1.7 fl oz
+67.3%Visible radiance*
−34.3%Pore volume*
BioRepair Hydrogel Mask 2 FREE BioRepair™ Hydrogel MasksWith every Dual Serum · automatically added at checkout FREE GIFT

Try the full-size treatment for up to 90 days. If it isn't right for your skin, you're covered.

90-day
guarantee
Clinically
tested
Free US
shipping $50+

Visible results · after one use

Immediate refinement.
Progressive resurfacing.

Model applying the two Dual Infushot formulas
+67.3%Visible radiance
−34.3%Pore volume

Independent third-party single-use instrumental test · women ages 40–60 · n=20

Why it works

Two active systems.
One treatment.

Target visible pores, uneven texture and lost radiance in one nightly treatment.

DERBIOME PDRN technology
DERBIOME®
PDRN + exosomes
HPR Retinoid Complex
HPR
Retinoid Complex
01 · Combine

Two active systems.
One complete treatment.

PDRN, exosomes and HPR Retinoid Complex work together to improve the visible look of pores, uneven texture and lost radiance.

Kept separate until the press, then applied as one treatment.
Dual Infushot formulas freshly combined in one press
02 · Renew

Renew. Refine.
Reveal.

One nightly treatment supports smoother-looking texture, visibly refined pores and renewed radiance.

Marine micro-spicule delivery visual
03 · Deliver

Micro-spicule
delivery.

Ultra-fine marine micro-spicules help create temporary pathways through the skin’s outermost layer, helping the freshly mixed treatment absorb more effectively.

Clinically measured · after one use
+67.3%Visible radiance
−34.3%Pore volume
−31.0%Pore area
−17.5%Pore count
−15.8%Pore depth
04 · Reveal

Visible change
after one use.

Five device-measured changes in radiance and visible pore dimensions after a single finished-product application.

01 / 04

*Mechanism description refers to the skin’s outermost layer. After-one-use results: device-measured in 20 women ages 40–60; radiance by SkinGlossmeter and pore metrics by Antera 3D. All changes versus baseline, p<0.05. ProbeM Skin Research Center, Korea, 2025. Individual results may vary.

Finished formula · clinical

Results you can see.

Before and after one use.

BeforeAfterBefore and after visible radiance after one use
+67.3%Visible radianceAfter one use
BeforeAfterBefore and after pore volume after one use
−34.3%Pore volumeAfter one use

*Independent third-party single-use clinical test in women ages 40–60 (n=20). Individual results may vary.

Clinical discipline

Built into the formula.

Dr. Donghyun Youn

Dr. Donghyun Youn

CISL CTO · Board-Certified Plastic Surgeon

Jamie Kim

Jamie Kim

PA-C Dermatology

Dr. Kim

Dr. Kim

Board-Certified Dermatologist

Developed with the logic of Korean clinical protocols, then tested as a finished cosmetic formula.

Real skin · real results

See what customers are saying.

Make it your protocol

Smoother, brighter,
more like yourself again.

Dual Infushot™ Serum · 50 mL

$119 Add to cart — $119
Dual Infushot Rejuvenation Serum

Not ready for full size?

Start with 14 days.

Evaluate the dual-formula protocol through 14 individually packed treatments.

14-Day Dual Infushot™ Trial Kit$19
Try the 14-day kit Limit 1 per order · Shipping calculated at checkout · Trial sizes are not covered by the 90-Day Guarantee.
CISL Dual Infushot 14-day trial kit

What makes the difference

Inside the system.

DERBIOME PDRN visual

Patented low-molecular-weight DERBIOME® PDRN

The rejuvenation core of Dual Infushot™, paired with exosomes in the renewal chamber.

HPR Retinoid Complex visual

HPR Retinoid Complex

A next-generation retinoid system that supports visibly refined texture and softer-looking lines.

Marine micro-spicules visual

Marine micro-spicules

Ultra-fine spicules support targeted application through the skin’s outermost layer. A temporary prickling sensation may occur.

Your nightly protocol

Dispense. Blend. Apply.

01Dispense + blendPress both pumps once and blend the two formulas together.
02Apply at nightSmooth over clean, dry skin. Follow with moisturizer as needed.
03Build graduallyBegin 2–3 nights weekly, increase as tolerated, and use sunscreen daily.
Retinoid + micro-spicule use

Avoid other retinoids or exfoliating acids on the same night. Do not apply to compromised or freshly treated skin. Temporary prickling may occur; reduce frequency if needed.

Frequently asked

The essentials.

Why are there two formulas?+

The PDRN + exosome and retinoid systems stay in separate chambers, then dispense together for each nightly application.

How should I begin using it?+

Start 2–3 nights per week and increase gradually as your skin adjusts. Use sunscreen every morning.

Can I use it with another retinoid?+

Avoid layering it with another retinoid or strong exfoliating acids on the same night.

Is the prickling sensation normal?+

A temporary prickling sensation can occur from the marine micro-spicules and may vary by person. Sensation does not indicate efficacy.

What is covered by the 90-day guarantee?+

Full-size purchases are covered by the 90-Day Money-Back Guarantee. Discovery kits are not eligible.

DUAL INFUSHOT™ REJUVENATION...$119