KOREAN PDRN + RETINOID DUAL TREATMENT

CISL DUAL INFUSHOT™ SERUM

★★★★★4.8 · 105 reviews

Smoother, firmer, more luminous-looking skin.

PDRN rejuvenation + retinoid renewal — powered by DERBIOME® PDRN.

$119· 50 mL / 1.7 fl oz

After one use: +67.3% visible radiance · −34.3% appearance of pores

or 4 interest-free payments of $29.75 withafterpay⟹

Try the full-size treatment for up to 90 days. If it isn't right for your skin, you're covered.

Dermatologist-Tested*
90-Day Guarantee
Free US Shipping $50+
CISL DUAL INFUSHOT™...$119

WHEN SKIN NO LONGER LOOKS QUITE THE SAME

Visible aging shows up in more than lines.

Skin can start to look rougher and less luminous, pores more visible, and firmness softer — and it may not bounce back the way it once did.

Uneven texture & visible pores
Fading radiance
Softer firmness & slower recovery
Makeup sits differently

“I want my skin to look smoother, brighter and more like itself again.”

What You'll See

Smoother
Texture

Firmer-Looking
Skin

Visible
Radiance

One Treatment, Two Kinds of Renewal

Smoother, firmer skin needs more than one approach.

Aging skin changes in more than one way. Renewal slows, visible resilience declines, and texture becomes less refined. One approach may not be enough.

PDRN Rejuvenation

Helps skin look firmer, smoother and more resilient.*

Powered by DERBIOME® PDRN

Retinoid Renewal

Refines uneven texture and softens the look of lines over time.*

Powered by HPR Retinoid
Dual-chamber system

DUOMIX™ Dual-Chamber System

Kept in separate chambers and dispensed together at use. Designed separately. Applied together.

Visible Results

Immediate refinement. Progressive rejuvenation.

After one use
After four weeks
BeforeAfter · 1 Use
+67.3%
Visible Radiance
After One Use*
−34.3%
Appearance of Pores
After One Use*
97%
Customer Satisfaction
After Four Weeks*

*Based on CISL clinical testing. Exact figures, study size and footnote wording to be finalized from the verified report.

Not Ready for Full Size?

Begin with the 14-Day Discovery Kit.

Experience the Dual Infushot™ treatment for 14 days before committing to full size.

14-Day Clinical Evaluation Kit
14-Day Discovery Kit
$19
Discover Dual — $19

Separate product. The 90-Day Guarantee applies to full-size only.

Swipe through the full technology set.

AGELOCK

AGELOCK™

Exosome support technology. Detailed wording to be finalized from verified data.*

Marine Spicules

Marine Spicules

Microneedling-inspired treatment technology. Dermatologist-tested for low irritation.*

HPR Retinoid

HPR Retinoid

Next-generation retinoid renewal for refined texture and softer-looking lines.*

DERBIOME PDRN

DERBIOME® PDRN

Patented low-molecular-weight PDRN — the rejuvenation core of Dual Infushot™.*

01 / 04

Reviewed & Trusted

Inspired by Korean between-treatment protocols.Tested as a finished formula.Explained by qualified experts.
Dr. Jamie Kim
Dr. Jamie Kim
PA, C-Dermatologist
Chelsea Kim
Chelsea Kim
PA, Nurse Practicioner
Dr. Zoe Indigo
Dr. Zoe Indigo
MD, Board Certified Dermatologist

Connected to the reviews app on publish — real reviewer name, badge, age, skin type and body. No placeholder names go live.

How to Use

One focused nighttime treatment.

1

Dispense both formulas.

Prime on first use, then dispense as directed.**

2

Apply at night.

Apply to clean, dry skin and follow with moisturizer.

3

Build gradually.

Start 2–3 nights per week and increase with tolerance.

Use sunscreen daily and avoid other retinoids or strong exfoliating acids on the same night. Use between professional treatments only after skin has fully recovered; do not apply to compromised or freshly treated skin.

Begin Your Protocol

Smoother, brighter, more like yourself again.

Add the full-size Dual Infushot™ treatment.

$119· 50 mL / 1.7 fl oz

Try the full-size treatment for up to 90 days. If it isn't right for your skin, you're covered.

Frequently Asked Questions

What is Dual Infushot™ Serum?
A dual-formula nighttime treatment combining PDRN rejuvenation and retinoid renewal in a dual-chamber system, powered by DERBIOME® PDRN technology.*
What is DERBIOME® PDRN?+
CISL’s patented low-molecular-weight PDRN technology and the rejuvenation core of Dual Infushot™.*
Why are there two formulas?+
PDRN rejuvenation and retinoid renewal do different jobs. Separate chambers keep each formula distinct until it is dispensed and applied together.
Why might I feel a prickling sensation?+
Ultra-fine marine spicules may create a faint, temporary prickling sensation on contact — an expected part of the Infushot™ experience. Dermatologist-tested for low irritation.* Sensation varies by person and is not a measure of efficacy.
Is it suitable for sensitive skin?+
The HPR retinoid is chosen for gentleness and the finished formula is dermatologist-tested for low irritation.* Introduce slowly and monitor tolerance.
How often should I use it?+
Start 2–3 nights per week and increase gradually based on skin tolerance.
Can I use it with another retinoid?+
Avoid other retinoids or strong exfoliating acids on the same night. Alternate on separate evenings.
Can I use it right after a professional treatment?+
Use only after skin has fully recovered. Do not apply to compromised or freshly treated skin.
How long does one bottle last?+
Approximately a 2-month supply with nightly use, depending on amount used.
What is covered by the 90-Day Guarantee?+
Full-size purchases are covered by our 90-Day Money-Back Guarantee. Discovery Kits are not eligible.

Complete the Protocol

Complete the recovery step.

Pair Dual Infushot™ with barrier-supporting recovery care after intensive treatment nights.

BIOBARRIER™ RECOVERY CAPSULE CREAM
BIOBARRIER™ RECOVERY CAPSULE CREAM
$79
Add
BioRepair™ Hydrogel Mask
BioRepair™ Hydrogel Mask
$49
Add